HYDROXYAPATITE DOLOMITE

Dolomite is a good source of natural calcium and magnesium in the natural Ca/Mg ratio of about 2:1. Calcium is a quantitative element and therefore does not belong to microelements. With a content of 1-1.1 kilograms, calcium is the most abundant mineral in the human body. 99% of calcium in the body is found in bones and teeth - the calcium-rich compound hydroxyapatite (Ca5(PO4)3(OH)) gives them stability and strength. At the same time, the bones serve as a reservoir for calcium - in case of calcium deficiency, some of it is released from the bones and made available for other tasks. The decalcification of bone tissue - osteoporosis - occurs mainly in old age. In cells, calcium is responsible for the excitation of muscles and nerves, glycogen metabolism and division, and participates in the activation of certain enzymes and hormones. There should be a constant concentration of 2.1-2.6 mmol/l calcium in the blood. It is regulated by hormones such as calcitriol or calcitonin. Only 0.1% of the total calcium content in the body is found in the extracellular space, of which 50% is in a freely ionized and therefore biologically active form. Calcium is involved in many metabolic processes, such as bone metabolism, neuromuscular excitability, nerve conduction and blood clotting. We need calcium the most during pregnancy, breastfeeding, during growth and for bone mineralization in old age. Since magnesium is essential for all organisms, it is one of the essential substances. Magnesium is found in varying amounts in all foods and in drinking water. It is absorbed in the upper part of the small intestine. The body of an adult contains about 20 grams of magnesium (compared to 1000 g of calcium). In blood plasma, magnesium is bound to 40% of proteins. Magnesium is involved in approximately 300 enzymatic reactions as an enzyme component or coenzyme, and in addition, free magnesium ions affect the cell membrane potential. Magnesium ions act as a "second messenger" in the immune system. They stabilize the resting potential of excitable muscle nerve cells and cells of the autonomic nervous system. Magnesium deficiency leads to restlessness, nervousness, irritability, headaches, lack of concentration, fatigue, general weakness, cardiac arrhythmias and muscle spasms.

Animal bones consist of up to about 65% inorganic components, mainly hydroxyapatite - a type of calcium phosphate with the formula Ca5[OH|(PO 4)3] and about 35% organic components, mainly collagen, which is a structural protein with very high tensile strength . In addition, they have proteins and fats, and fresh bones and water. Hydroxyapatite provides bones with compressive strength and stiffness, and collagen with tensile strength. Hydroxyapatite can form in certain cells, the so-called osteoblasts, from phosphate and calcium ions. For this purpose, phosphate ions are initially released in a collagen matrix of organic phosphates until the solubility product of calcium phosphate is exceeded. Collagen acts as a nucleus for the crystallization of hydroxyapatite. The high strength results from the fact that the hydroxyapatite crystals line up along the lines of tensile and compressive stress and in doing so form a strut structure. Hydroxyapatite is an important building block for the development of bone tissue. For example, the bones of the skeleton consist of about 50%, dentin (the substance of which teeth are made up) of about 70%, and tooth enamel - of about 97% hydroxyapatite. Our calcium hydroxyapatite is entirely bovine bone extract. This extract contains the same unique bone component - hydroxyapatite - that the body needs to restore lost bone tissue. The extract is obtained by freeze-drying at extremely low temperatures, which preserves bone material and organic bone growth factors.

Cholecalciferol (or Calciol for short), vitamin D3 is the physiologically occurring vitamin D in all non-plant eukaryotes and, accordingly, in humans. In food, it is mainly found in fish or added to food as a food additive. In the body, it assumes the function of a precursor and through an intermediate stage is converted into calcitriol. Vitamin D plays an important role in regulating blood calcium levels and bone structure. Vitamin D deficiency leads in the medium term to childhood rickets, and in adults to osteomalacia/osteoporosis. Since the 1990s, vitamin D has been shown to have functions in a variety of other tissues that include cell differentiation, inhibition of cell proliferation, apoptosis (cell death), immune modulation, and control of other systems. Vitamin D deficiency, according to the results of previous studies, is a risk factor for autoimmune diseases, such as multiple sclerosis, Crohn's disease, diabetes mellitus type 1), infectious diseases, high blood pressure, cardiovascular diseases, metabolic syndrome, muscle weakness, dementia, Parkinson's disease and disorders of the effective functioning of the brain. Vitamin D is protective against various types of cancer, such as breast cancer, leukemia, kidney cancer, ovarian cancer, and pancreatic cancer. In addition, vitamin D may reduce the number of falls in people over 65. Taking 700-1000 IU reduces the risk of falling by 19%.